Cipol N 25 mg 50 Capsules

Manufacturer	High-Q Pharmaceuticals Pakistan
Active Ingredients	Ciprofloxacin and Nitazoxanide
Medicine Strength	500mg Ciprofloxacin + 500mg Nitazoxanide per Tablet
Formulation	Film-Coated Tablets
Requires Prescription?	Yes
Generics	Ciprofloxacin + Nitazoxanide

Cipol-N Ingredients and Usage

The active ingredients are Ciprofloxacin (fluoroquinolone antibiotic) and Nitazoxanide (antiprotozoal agent). The combination tablet is taken orally with food for gastrointestinal infections. Cipol-N is clinically indicated for:

• Bacterial diarrhea and gastroenteritis
• Protozoal infections including giardiasis
• Mixed bacterial and parasitic gastrointestinal infections
• Traveler's diarrhea management

How Does Cipol-N Work?

Cipol-N provides dual antimicrobial action through different mechanisms:

1. DNA Gyrase Inhibition: Ciprofloxacin blocks bacterial DNA replication
2. Pyruvate Fermentation Interference: Nitazoxanide disrupts parasite energy metabolism
3. Broad Spectrum Coverage: Targets both bacterial and protozoal pathogens
4. Synergistic Action: Combined effect enhances treatment efficacy

Cipol-N Side Effects and Warnings

Common side effects include nausea, abdominal pain, headache, and dizziness. Most reactions are mild and self-limiting.

Serious Considerations

1. Tendon Damage: Ciprofloxacin may cause tendonitis and tendon rupture
2. CNS Effects: Risk of seizures, dizziness and psychiatric reactions
3. Hypersensitivity: Serious allergic reactions including anaphylaxis
4. Drug Interactions: Antacids and iron supplements reduce absorption
5. Hepatic Impairment: Use with caution in patients with liver disease

Cipol-N Storage Conditions

Cipol-N Tablets require proper storage conditions:

• Store at room temperature below 30°C
• Keep in original packaging, protected from moisture
• Protect from light and excessive heat
• Keep out of reach of children
• Do not use after the expiration date