Crespine Gel Plus

Manufacturer	BioPolymer
Active Ingredients	Cross-linked Hyaluronic Acid, Non-crosslinked Hyaluronic Acid, Prilocaine
Medicine Strength	20mg/mL HA with 3mg/mL Prilocaine
Formulation	Sterile Gel for Dermal Injection
Requires Prescription?	Yes (Dermatologist/Aesthetic Physician use only)
Generics	Hyaluronic Acid + Prilocaine combination

Crespine Gel Plus Ingredients and Usage

The active ingredients include cross-linked HA for longevity, non-crosslinked HA for hydration, and prilocaine for local anesthesia. The gel is administered via intradermal injection by qualified practitioners. Crespine Gel Plus is clinically indicated for:

• Facial wrinkles and fold correction
• Lip augmentation and enhancement
• Facial contouring and volume restoration
• Dermal hydration and skin quality improvement

How Does Crespine Gel Plus Work?

Crespine Gel Plus provides dual action through tissue augmentation and pain management:

1. Tissue Volumization: Cross-linked HA provides structural support and volume
2. Hydration Enhancement: Non-crosslinked HA binds water for skin moisturization
3. Pain Control: Prilocaine blocks sodium channels for local anesthesia
4. Biocompatibility: Hyaluronic acid integrates naturally with skin tissues

Crespine Gel Plus Side Effects and Warnings

Common side effects include temporary redness, swelling, bruising, and tenderness at injection sites. Most reactions resolve within days.

Serious Considerations

1. Vascular Complications: Risk of vascular occlusion requiring immediate treatment
2. Hypersensitivity: Possible allergic reactions to lidocaine analogues
3. Infection Risk: Strict aseptic technique required during administration
4. Product Placement: Correct depth and technique essential for optimal results
5. Medical History: Screen for bleeding disorders and autoimmune conditions

Crespine Gel Plus Storage Conditions

Crespine Gel Plus requires specialized storage handling:

• Store refrigerated between 2°C and 8°C
• Do not freeze - protect from freezing temperatures
• Keep in original packaging until use
• Use immediately after opening
• Discard unused product after single use