Daclaget 60mg 28's Tablets

Manufacturer	Getz Pharma Pakistan
Active Ingredients	Daclatasvir Dihydrochloride
Medicine Strength	60mg per Tablet
Formulation	Film-Coated Tablets
Requires Prescription?	Yes (Gastroenterologist/Hepatologist prescription)
Generics	Daclatasvir

Daclaget Ingredients and Usage

The active ingredient is Daclatasvir Dihydrochloride, an NS5A replication complex inhibitor. The 60mg tablet is taken once daily with or without food in combination with other antivirals. Daclaget is clinically indicated for:

• Chronic hepatitis C genotype 1, 2, 3 and 4 infections
• Treatment-naïve and treatment-experienced patients
• Combination therapy with sofosbuvir
• Patients with compensated liver cirrhosis

How Does Daclaget Work?

Daclaget provides targeted antiviral action through specific mechanisms:

1. NS5A Inhibition: Blocks hepatitis C virus NS5A protein function
2. Viral Replication Suppression: Prevents viral RNA replication and assembly
3. Multi-genotypic Activity: Effective against multiple hepatitis C genotypes
4. High Barrier to Resistance: Maintains efficacy despite viral mutations

Daclaget Side Effects and Warnings

Common side effects include headache, fatigue, nausea, and diarrhea. Most reactions are mild and transient during treatment.

Serious Considerations

1. Drug Interactions: Strong CYP3A inducers reduce daclatasvir levels
2. Hepatitis B Reactivation: Screen for HBV coinfection before treatment
3. Bradycardia Risk: When used with amiodarone and sofosbuvir
4. Liver Function: Monitor transaminases during therapy
5. Treatment Duration: Varies based on genotype and prior treatment history

Daclaget Storage Conditions

Daclaget Tablets require proper storage conditions:

• Store at room temperature below 30°C
• Keep in original packaging protected from moisture
• Protect from light and excessive heat
• Keep out of reach of children
• Do not use after expiration date