Eltrom 25mg Tablets 28S

Manufacturer	Getz Pharma Pakistan
Active Ingredients	Eltrombopag Olamine
Medicine Strength	25mg per Tablet
Formulation	Film-Coated Tablets
Requires Prescription?	Yes (Hematologist prescription required)
Generics	Eltrombopag

Eltrom Ingredients and Usage

The active ingredient is Eltrombopag Olamine, identical to Revolade formulation. The 25mg tablet is taken once daily on an empty stomach at least 1 hour before or 2 hours after food. Eltrom is clinically indicated for:

• Chronic immune thrombocytopenia in adult patients
• Patients who have insufficient response to corticosteroids
• Thrombocytopenia in chronic hepatitis C patients
• Severe aplastic anemia treatment

How Does Eltrom Work?

Eltrom provides targeted platelet stimulation through specific mechanisms:

1. TPO Receptor Activation: Binds to human thrombopoietin receptor
2. Megakaryocyte Growth: Stimulates bone marrow megakaryocyte proliferation
3. Platelet Production: Increases circulating platelet counts
4. JAK-STAT Pathway: Activates intracellular signaling cascades

Eltrom Side Effects and Warnings

Common side effects include headache, nausea, diarrhea, and elevated liver enzymes. Most reactions are mild to moderate and manageable.

Serious Considerations

1. Hepatotoxicity: Regular liver function monitoring essential
2. Bone Marrow Fibrosis: Risk of increased reticulin formation
3. Thrombotic Risk: Blood clot risk with elevated platelet counts
4. Cataract Development: Regular ophthalmological examinations needed
5. Drug Interactions: Chelates with polyvalent cations affecting absorption

Eltrom Storage Conditions

Eltrom Tablets require proper storage conditions:

• Store at room temperature below 30°C
• Keep in original packaging protected from moisture
• Protect from light and excessive heat
• Keep out of reach of children
• Do not use after expiration date